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Inseminations can be used under several different circumstances.
Parameters have been very well defined as to what constitutes a
normal semen analysis. What options have a reasonable chance of
success if the sperm count is compromised have also been well defined.
We know, for example, that approximately ten million sperm are needed
for inseminations to have a reasonable chance of success. Significantly
lower sperm counts dictate consideration of more aggressive alternatives
such as IVF and perhaps even ICSI. The first indication for inseminations
is, therefore. compromised sperm counts. Inseminations also allow
us to monitor the sperm count and be sure that continued attempts
with insemination are warranted.
Inseminations are also indicated if there is, for some reason,
decreased cervical mucus production. This can occur if there has
been prior treatment of cervical dysplasia such as a LEEP procedure
or laser therapy. Decreased cervical mucus production is also encountered
frequently in women treated with clomiphene. (We, howeveer, do not
use clomiphene except in very unusual circumstances.)
If anti-sperm antibodies are present, insemination is a good alternative.
The vast majority of the antibodies to the sperm are prodcued by
the cervix and expressed in the cervical mucus. Insemination bypasses
the cervix, making anti-sperm antibodies a non-issue.
Perhaps most importantly,intercourse-on-demand gets old very quickly.
The stress of "having to have sex" at specfied times on
specified days takes a toll on the individuals and, sometimes, on
the marriage itself. We therefore, often recommend inseminations
as a means of obviating this issue. Most couples find insemination
much less stressful than intercourse-on-demand.
Inseminations are more successful than is timed intercourse. This
has been clearly shown in several studies. It has also been shown
that two inseminations are more successful than one if the problem
is a somewhat compromised sperm count, and the optimal timing seems
to be 18 and 42 hours after hCG administration (to trigger ovulation).
If the problem is endometriosis or unexplained infertility, one
insemination has a success rate that is as good as two. Therefore,
most commonly under these conditions we will recommend one insemination.
Our approach is this: If we are using ovulation induction, and
if there are no other mitigating factors, we will often allow a
couple to try to conceive with timed intercourse in the first cycle
of ovulation induction. If that initial attempt is unsuccessful
and we are going to attempt it again, we suggest inseminations as
a means of improving the likelihood of success. If logistically
feasible, we prefer to do two inseminations with timing as noted
above. If two inseminations are not feasible, we do one at about
30-32 hours after hCG administration.
© 2005 Jarrett Fertility Group |