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Technically
known as leiomyomas, fibroids are benign (99+% of the time) muscle
tumors that grow in the uterus. No one knows what causes fibroids,
but there certainly is good evidence that there is a genetic predisposition.
If your mother or sister has them, you are more likely to. Fibroids
may be very small or extremely large, ranging in size from pea size
to as big as a grapefruit or larger. They can also be solitary or
numerous. Thye can also be defined as pedunculated, sub-serosal,
intra-myometrial, sub-mucosal, or intra-cavitary. Pedunculated
firoids are those that literally hang from a stalk from the surface
of the uterus. Sub-serosal and intra-myometrial typically
do not distort the uterine cavity. Sub-mucosal fibroids distort
the uterine cavity, and intra-cavitqry are within the uterine cavity.
Most
fibroids do not cause difficulty conceiving. However, there are
exceptions. A large fibroid that distorts pelvic anatomy so that
the fallopian tubes cannot function properly can certainly be significant.
Also, any fibroid that distorts the uterine cavity can be a problem.
If
a fibroid distorts the uterine cavity enough that the distortion
can be seen on SIS, X-ray, or hysteroscopy, it has probably compromised
the blood supply to the endometrium that overlies it. If this blood
supply is compromised, this tissue cannot function properly and
undergo all of the changes that it should, and it may not be able
to allow implantation. Fibroids can also be pedunculated, or hanging
into the uterine cavity from a stalk. The uterus does not like having
anything in it with the exception of a fetus. Fibroids in the uterine
cavity can result in much the same effect that occurs with an IUD
- they irritate the uterus enough that it will not allow implantation
to occur. Fibroids that distort the uterine cavity may be associated
with bleeding at times other than the normal period. Consideration
should be given to removing any fibroid within the uterine cavity
or that distorts the uterine cavity.
There
are now several techniques available for treating fibroids, but
the gold standard still remains surgical removal. Most
sub-mucosal and intra-cavitary fibroids can be removed via hysteroscopy,
a minor outpatient surgcal procedure in whcihc a small telescope
like instrument is placed through the cervix, the fibroid visualized
and removed.
Pedunculated
and sub-serosal fiboids can often be removed via laparascopy.
Laparoscopic removal has the advantage of a much shorter post-operative
recovery with less pain than a major surgical procedure (laparotomy).
However, there are limitations as to which fibroids should be removed
laparoscopically. The biggest risk of myomectomy is uterine
rupture during subsequent pregnancy. For this reason, great
care is taken at the time of myomectomy to reapproximate the remaining
muscle of the uterus that surrounded the firboids. This requires
that the muscle be very carefully sutured. There is no question
that suturing of large defects can be most adequately perfomed at
the time of laparotomy. Therefore, if a significant defect
in the muscle of the uterus results from removal of the fibroid,
laparotomy is the approach of choice.
Depo-Lupron
can be used to medically shrink fibroids. This is, however,
temporary and upon discontinuation of the lupron the fibroids will
return to their previous size. The only time that lupon is
of real value is in individuals who are anemic, or who need to postpone
surgery for one reason or another. Lupron in these circumstances
allows us to delay surgery without further bleeding or growth of
the fiboids. Fibroids do shrink as a result of treatment with
Lupron, but this change in size is, most of the time, not enough
to justify the cost and side-effects of lupron use.
Embolization
is a technique that has gained recent favor for treating fibroids.
In an embolization procedure, the blood vessels that supply the
fibroid are occluded. Without adequate blood supply, the fibroids
shrink or regress completely. This is not, however, an option
for women who wish to preserve their child-bearing potential.
There have been case reports of uterine rupture during pregnancy
in women who have had embolization.
The
risks of myomectomy include bleeding, infection, formation of scar
tissue, and uterine rupture during pregnancy. Bleeding is
very rarely an issue in the hands of an experienced surgeon.
The same is true for infection. There are many steps taken
during this surgical procedure to prevent scarring. This includes
meticulous surgical technique, copious irrigation, and the use of
adhesion barriers. With appropriate technique, uterine rupture
is an extremely rare event. If removal of the fibroid(s) does
result in entry into the uterine cavity, the subsequent delivery
should be by cearean section. Otherwise, normal vaignal delivery
can be anticipated. Once removed, fibroids do not recur.
Other fibroids may grow, but removal is definitive treatment.
© 2005 Jarrett Fertility Group |